U (Adjective) — (chiefly British) of or appropriate to the upper classes especially in language use.
U (Noun) — The 21st letter of the Roman alphabet.
U (Noun) — A base containing nitrogen that is found in RNA (but not in DNA) and derived from pyrimidine; pairs with adenine.
U (Noun) — A heavy toxic silvery-white radioactive metallic element; occurs in many isotopes; used for nuclear fuels and nuclear weapons.