Santiago (Noun) — A naval battle in the Spanish-American War (1898); the United States fleet bottled up the Spanish ships in the harbour of Santiago de Cuba and destroyed them when they tried to escape.
Santiago (Noun) — A port city in southeastern Cuba; industrial centre.
Santiago (Noun) — City in the northern Dominican Republic.
Santiago (Noun) — The capital and largest city of Chile; located in central Chile; one of the largest cities in South America.